Analysis Of Aspirin Tablets

September 27, 2017 September 1st, 2019 Free Essays Online for College Students

The constraint given to us by the teacher was that, we had to determine, which from the three brands of Aspirin given represents the best value for money and worth purchasing? , Using a standard solution of Sodium Hydroxide (NaOH).

C6H5(OCOCH3)COOH + NaOH –> C6H5(OCOCH3)COO Na + H2O .

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(aq) (aq) (aq) (l)

Hypothesis

Aspirin drug is the most common medicine that is taken by people, from its history salicylic acid was used as a medium of painkiller and fever depressant. Because of it being strong, salicylic acid can damage the oesophagus and stomach membranes. As time passed the compound was modified and making it safer to intake thus making it more effective. Which is what we now call as Aspirin. The effectiveness of this tablet may depend on the mass of the tablet; this is because the tablet with more mass will have more the amount of Aspirin (C9 H8 O4) that is required to cure the fever and pain in the body, thus the price will be high because of its effectiveness. Therefore the power of the tablet to fight the fever and pain will increase with the amount of Aspirin. By titration of NaOH solution to the Aspirin solution, until there is a color change that shows the completion of the reaction. This helps to determine the amount of Aspirin (C9 H8 O4) and to know which tablet represents the best value for money.

Variables

Independent – Mass of different brands of Aspirin tablets

– Concentration of NaOH solution.

Dependent – Volume of the neutralized solution

– Time taken for Aspirin to dissolve in distilled water

Controlled – Same tablets

Apparatus used for the experiment were as follows

– Conical flask

– Burette -Bunsen burner & Tripod stand

– Motor and pestle – Weighing Scale

Materials used for the experiment

– A standard solution of Sodium Hydroxide (NaOH)

– 3 different Brands of Tablets

– Phenolphthalein Indicator

Procedure

– Choose a brand of tablet, note the brand and price per tablet and weight it.

– Crush tablet using motor and pestle and rinse the power using distilled water in a conical flask

– Add more distilled water until approximately 25 cubic cm.

– Warm the solution, so as the tablet dissolves faster.

– Add 3-4 drops of phenolphthalein indicator.

– Titrate the Aspirin solution with 0.05mol per dm cube of NaOH

– And record the reading

– Repeat with another brand of tablet .

Data collection

The result were obtained as follows,

Tablets

Mass of tablet weighed in grams

(� 0.05 g)

Concentration of NaOH in mol per dm cube

Volume of NaOH used in the burette.

(� 0.05 cm3)

Volume of NaOH Titered in with Aspirin .sol

(� 0.005 cm3)

Shelly’s

300mg

0.40 g

0.05

50cm3

42.90cm3

Tamilnadu

300mg

0.34g

0.05

50cm3

34.80cm3

Tablet 3

350 mg

0.55g

0.05

50cm3

30.20cm3

Data Processing and presentation

From the data obtained above , shows that 0.05molperdm cube and the volume titrated of NaOH react with the aspirin solution to form a neutralization reaction .

Conclusion and Evaluation

Conclusion: – From the Observation of the resulting data, the percentage purity of the third tablet is greater than the other two tablets. This explains that the third tablet will be more effective than the others because of its having the maximum pure part of the compound that helps to cure the fever and pain. Thus representing the best value for money and worth purchasing.

Evaluation: – Basically, my hypothesis showed itself to work well, the experiment was effective and a result we received the volume of the NaOH used of which we had to find the number of moles and then calculation the theoretical results, and using all the information we had to calculate the percentage purity that would determine which Aspirin tablet represent the best value for money.

However I discovered that the result I got resembled with my partner and other students as well, therefore I was convinced that I was on the right track.

Improvements:

1: We could have performed few more tests with different amount of Aspirin tablets. However time was limited and we settled with a sensible result.

2: We could have made our work a bit fast so we could make further testing even though we had enough results we needed.

Manipulating skills:

We were carefully following every instruction given by the teacher on a piece of paper. We used the materials need in an amount that was needed and not wasting them by taking large amounts. And finish our experiment successfully with sensible results that would help us understand with out any damage .

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